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Models List

View all available models

To view all available models for your current installation of dorado use:

dorado download --list

This page contains the list of available simplex and modified basecalling models.

Please read important information on Understanding Model Names especially the section on Model Version Numbers.

The bolded models are for the latest released condition.

Deprecated models

The DNA R9.4.1 and RNA002 models were deprecated in Dorado v1.0.0 release.

Help on basecalling legacy conditions.

DNA Models

Basecalling Models Compatible
Modifications		 Modifications
Model
Version		 Data
Sampling
Frequency
dna_r10.4.1_e8.2_400bps_fast@v5.2.0 5 kHz
dna_r10.4.1_e8.2_400bps_hac@v5.2.0 4mC_5mC
5mCG_5hmCG
5mC_5hmC
6mA
 v1
v1
v1
v1		 5 kHz
dna_r10.4.1_e8.2_400bps_sup@v5.2.0 4mC_5mC
5mCG_5hmCG
5mC_5hmC
6mA
 v1
v1
v1
v1		 5 kHz
dna_r10.4.1_e8.2_400bps_fast@v5.0.0 5 kHz
dna_r10.4.1_e8.2_400bps_hac@v5.0.0 4mC_5mC
5mCG_5hmCG
5mC_5hmC
6mA
 v3
v3
v3
v3		 5 kHz
dna_r10.4.1_e8.2_400bps_sup@v5.0.0 4mC_5mC
5mCG_5hmCG
5mC_5hmC
6mA
 v3
v3
v3
v3		 5 kHz
dna_r10.4.1_e8.2_400bps_fast@v4.3.0 5 kHz
dna_r10.4.1_e8.2_400bps_hac@v4.3.0 5mCG_5hmCG
5mC_5hmC
6mA
 v1
v1
v2		 5 kHz
dna_r10.4.1_e8.2_400bps_sup@v4.3.0 5mCG_5hmCG
5mC_5hmC
6mA
 v1
v1
v2		 5 kHz
dna_r10.4.1_e8.2_400bps_fast@v4.2.0 5mCG_5hmCG v2 5 kHz
dna_r10.4.1_e8.2_400bps_hac@v4.2.0 5mCG_5hmCG v2 5 kHz
dna_r10.4.1_e8.2_400bps_sup@v4.2.0 5mCG_5hmCG
5mC_5hmC
5mC
6mA
 v3.1
v1
v2
v3		 5 kHz

RNA Models

Warning

The BAM format does not support U bases.

Therefore, when Dorado is performing RNA basecalling, the resulting output files will include T instead of U. This is consistent across output file types.

The same applies to parsing inputs. Any input HTS file (e.g. FASTQ generated by guppy/basecall_server) with U bases is not handled by Dorado.

Basecalling Models Compatible
Modifications		 Modifications
Model
Version		 Data
Sampling
Frequency
rna004_130bps_fast@v5.2.0 4 kHz
rna004_130bps_hac@v5.2.0 m5C
m6A_DRACH
inosine_m6A
pseU		 v1
v1
v1
v1		 4 kHz
rna004_130bps_sup@v5.2.0 m5C_2OmeC
m6A_DRACH
inosine_m6A_2OmeA
pseU_2OmeU
2OmeG		 v1
v1
v1
v1
v1		 4 kHz
rna004_130bps_fast@v5.1.0 4 kHz
rna004_130bps_hac@v5.1.0 m5C
m6A_DRACH
inosine_m6A
pseU		 v1
v1
v1
v1		 4 kHz
rna004_130bps_sup@v5.1.0 m5C
m6A_DRACH
inosine_m6A
pseU		 v1
v1
v1
v1		 4 kHz
rna004_130bps_fast@v5.0.0 4 kHz
rna004_130bps_hac@v5.0.0 m6A
m6A_DRACH
pseU		 v1
v1
v1		 4 kHz
rna004_130bps_sup@v5.0.0 m6A
m6A_DRACH
pseU		 v1
v1
v1		 4 kHz
rna004_130bps_fast@v3.0.1 4 kHz
rna004_130bps_hac@v3.0.1 4 kHz
rna004_130bps_sup@v3.0.1 m6A_DRACH v1 4 kHz